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Protein Coding Gene : Cfap157 cilia and flagella associated protein 157
Primary Identifier  MGI:2447809 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  227736
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables microtubule binding activity. Involved in sperm axoneme assembly. Located in ciliary basal body. Is expressed in several structures, including genitourinary system; nasal epithelium; node; respiratory system; and snout. Orthologous to human CFAP157 (cilia and flagella associated protein 157).
PHENOTYPE: Homozygous knockout males are infertile owing to reduced sperm count and reduced and abnormal sperm motility as a result of abnormal sperm morphology. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1700019L03 gene,
  • Cfap157,
  • 1700019L03Rik,
  • cilia and flagella associated protein 157
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