Primary Identifier | MGI:5638671 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Arhgef28 |
Transmission | Germline | Strain of Origin | (C57BL/6NTac x 129S6/SvEvTac)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A floxed neomycin resistance cassette was inserted upstream of exon 24. An additional loxP site was inserted downstream of exon 24. Cre-mediated recombinated removed the selection cassette and exon 24. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts. |