|  Help  |  About  |  Contact Us

Allele : Nfkb1<tm1Brv> nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105; targeted mutation 1, Rodrigo Bravo

Primary Identifier  MGI:2179707 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nfkb1
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette was inserted into the gene, disrupting the carboxy terminal domain of the encoded protein. Western blot analysis on lystates derived from thymus of homozygous mice confirmed that the p50 isoform of the protein was expressed, but the p105 precursor was not detectable.
  • mutations:
  • Insertion
  • synonyms:
  • NF-kappaB KO,
  • p50,
  • p105 -,
  • p50,
  • NF-kappaB KO,
  • p105 -,
  • Nfkb1<deltaCT>,
  • Nfkb1<deltaCT>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories

Trail: Allele