Primary Identifier | MGI:3785001 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Cma1-cre)XRoer |
Strain of Origin | C57BL/6 | Is Recombinase | true |
Is Wild Type | false |
molecularNote | This transgene contains a modified BAC RP23-284A14 in which a cre and floxed neo cassette was inserted into exon 1 replacing a portion of the coding region. Cre-mediated deletion was used to remove the neo cassette. Six founder lines were generated one with only 80% of peritoneal mast cells expressing the transgene that was not further examined and two other lines expressing in 100% of peritoneal cells in an autosomal inheritance pattern (line A) and the other in an X-linked inheritance pattern (line X). |