| Primary Identifier | MGI:1859631 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 54635 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables platelet-derived growth factor receptor binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including platelet-derived growth factor receptor signaling pathway; positive regulation of fibroblast proliferation; and regulation of peptidyl-tyrosine phosphorylation. Located in extracellular region. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human PDGFC (platelet derived growth factor C). PHENOTYPE: Homozygous mutation of this gene results neonatal and postnatal lethality with cleft palate, hypoplastic palatine bones, edema, blistering, and a short nasal septum with one allele or abnormal retinal pigmentation with a second allele. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
