Primary Identifier | MGI:3664103 | Allele Type | Spontaneous |
Gene | Atp2b2 | Strain of Origin | DSO |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An intracisternal A particle (IAP) was found to have inserted at the downstream donor splice site of exon 1. Primary transcripts are prematurely terminated and a chimeric mRNA including fused IAP sequence is produced. Expression of full length mRNA is reduced to about 5% of normal. Expression of full length and chimeric mRNA is reduced to about 60% relative to controls. |