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Allele : Kmt2d<em1Kaig> lysine (K)-specific methyltransferase 2D; endonuclease-mediated mutation 1, Kai Ge
Primary Identifier  MGI:7565499 Allele Type  Endonuclease-mediated
Gene  Kmt2d Strain of Origin  (C57BL/6J x DBA/2J)F1/J
Is Recombinase  false Is Wild Type  false
molecularNote  Tyrosine codon 5477 (TAC) in exon 52 was changed to alanine (GCT) (p.Y5477A) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation creates a enzyme-dead version of the encoded peptide.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • MLL4 Y5477A,
  • Mll4<KI>,
  • Mll4<KI>,
  • MLL4 Y5477A
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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