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Allele : F2r<tm1Ajc> coagulation factor II thrombin receptor; targeted mutation 1, Andrew J Connolly

Primary Identifier  MGI:1857306 Allele Type  Targeted
Attribute String  Null/knockout Gene  F2r
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced sequences in exon 2 encoding transmembrane domains 1-7. Northern blot analysis on RNA derived from E12 embryos and from embryonic fibroblasts demonstrated that no detectable transcript was produced from this allele. Furthermore, transcripts from this allele were not detected in various tissues of adult homozygous mice (data not shown).
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Par1<->,
  • PAR-1<->,
  • Par1-,
  • Par1-,
  • tr-,
  • PAR-1<->,
  • Par1<->,
  • tr-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

Trail: Allele

0 Driven By

76 Publication categories

Trail: Allele