First Author | Nishi M | Year | 1994 |
Journal | Biochem Biophys Res Commun | Volume | 205 |
Issue | 2 | Pages | 1353-7 |
PubMed ID | 7802669 | Mgi Jnum | J:22019 |
Mgi Id | MGI:69913 | Doi | 10.1006/bbrc.1994.2814 |
Citation | Nishi M, et al. (1994) Structure and chromosomal mapping of genes for the mouse kappa-opioid receptor and an opioid receptor homologue (MOR-C). Biochem Biophys Res Commun 205(2):1353-7 |
abstractText | Recent cDNA cloning studies have defined four members of the opioid receptor family, i.e., delta-, mu- and kappa-subtypes, and an opioid receptor homologue for unknown ligands. In this report, we isolated and analyzed mouse genomic DNA segments containing the kappa-opioid receptor gene and a gene for the opioid receptor homologue (designated as MOR-C). The genes are closely related each other in exon-intron organization, suggesting their evolutional relationship. Using in situ hybridization, we show that the kappa-opioid receptor gene and the MOR-C gene map to mouse chromosome 1A2-3 and 2H2-4, respectively. |