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Allele : Ryr3<tm1Vso> ryanodine receptor 3; targeted mutation 1, Vincenzo Sorrentino

Primary Identifier  MGI:2181794 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ryr3
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 6 was replaced with a neomycin resistance gene via homologous recombination resulting in the deletion of the transmembrane domain containing carboxy terminus of the protein. Western blot analysis of microsomal proteins from diaphram muscles confirmed the absence of gene expression in homozygous mutant animals.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • RyR3<->,
  • RyR3<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

14 Publication categories

Trail: Allele