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Protein Coding Gene : Ralgapa2 Ral GTPase activating protein, alpha subunit 2 (catalytic)

Primary Identifier  MGI:3036245 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  241694
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables GTPase activator activity. Acts upstream of or within Ral protein signal transduction; regulation of exocyst localization; and regulation of protein localization. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm. Is expressed in cochlea; diencephalon lateral wall ventricular layer; midbrain ventricular layer; olfactory cortex mantle layer; and olfactory epithelium. Orthologous to human RALGAPA2 (Ral GTPase activating protein catalytic subunit alpha 2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased incidence and severity of induced urothelial bladder tumors. [provided by MGI curators]
  • synonyms:
  • Ral GTPase activating protein, alpha subunit 2 (catalytic),
  • RGC2,
  • A230067G21Rik,
  • RIKEN cDNA A230067G21 gene,
  • BC053994,
  • Ralgapa2,
  • AS250,
  • cDNA sequence BC053994,
  • MGI:2681868

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For