Primary Identifier | MGI:1345280 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 22784 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables zinc ion transmembrane transporter activity. Involved in zinc ion import into synaptic vesicle. Acts upstream of or within positive regulation of transport. Located in hippocampal mossy fiber and synaptic vesicle membrane. Is active in glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; and microvesicle. Is expressed in several structures, including brain; metanephros; olfactory nerve; and spinal cord mantle layer. Orthologous to human SLC30A3 (solute carrier family 30 member 3). PHENOTYPE: While zinc is absent from synaptic vesicles in homozygous null mice, inactivation of this locus does not affect brain morphology. [provided by MGI curators] |