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Allele : Tcf3<tm1(TCF3/HLF)Homy> transcription factor 3; targeted mutation 1, Hiroaki Honda
Primary Identifier  MGI:4458115 Allele Type  Targeted
Gene  Tcf3 Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  The coding regions of exon 2 and 3 were replaced with a floxed STOP cassette, human cDNA of a fusion between TCF3 and HLF, IRES-EGFP, and SV40 polyadenylation sequence. The fusion was identified in patients with t(17;19) B-lineage acute lymphoblastic leukemia (ALL). Cre mediated removal of the floxed STOP cassette is required to obtain expression of the fusion cDNA.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • EHKI<Neo+>,
  • EHKI<Neo+>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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