Primary Identifier | MGI:1276107 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 17389 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable metalloaminopeptidase activity; metalloendopeptidase activity; and zinc ion binding activity. Acts upstream of or within chondrocyte proliferation; collagen catabolic process; and skeletal system morphogenesis. Predicted to be located in extracellular matrix and membrane. Predicted to be active in extracellular space and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; skin; and visual system. Orthologous to human MMP16 (matrix metallopeptidase 16). PHENOTYPE: Mice homozygous for a gene disruption display normal morphology, clinical chemistry, hematology, and behavior. Mice homozygous for a null allele exhibit reduced skeletal growth. [provided by MGI curators] |