Primary Identifier | MGI:3044681 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 330319 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable SH3 domain binding activity; alpha-tubulin binding activity; and gamma-tubulin binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation; endosomal transport; and exocytosis. Is active in synapse. Orthologous to human WIPF3 (WAS/WASL interacting protein family member 3). PHENOTYPE: Mice homozygous for a knock-out allele display impaired spermatogenesis, abnormal sperm head morphology, and significantly reduced male fertility. Female fertility is not affected. [provided by MGI curators] |