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Allele : Trem2<em1Gbu> triggering receptor expressed on myeloid cells 2; endonuclease-mediated mutation 1, Guojun Bu
Primary Identifier  MGI:7539739 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Trem2
Strain of Origin  (C57BL/6J x DBA/2J)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR-targeting introduced the mutation responsible for the amino acid substitution histidine with tyrosine at position 157 (H157Y).
  • mutations:
  • Single point mutation
  • synonyms:
  • Trem2 H157Y,
  • Trem2 H157Y
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories





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