| Primary Identifier | MGI:5142235 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Pcp2-TBP*)69Hmhl |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| description | Four lines were made in J:174239, lines 20, 54, 69, and 71. |
| molecularNote | This transgene consists of the full-length human TATA box binding protein, TBP, with the 36 CAA/CAG repeat region expanded to 109 repeats under the control of the mouse Pcp2 promoter. A copy number of 10-20 is seen for line 69. Expression of the transgene occurs mainly in the cerebellum and brainstem, and at lower levels in cortex and hippocampus. |
