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Allele : Atoh1<tm1.1(cre/ERT2,-CD2)Dwi> atonal bHLH transcription factor 1; targeted mutation 1.1, Douglas J Winton

Primary Identifier  MGI:7444367 Allele Type  Targeted
Attribute String  Epitope tag, Inducible, Recombinase Gene  Atoh1
Transmission  Germline Strain of Origin  Not Specified
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  The targeting construct was designed to introduce a loxP site into 5'UTR of Atoh1, followed by the wild type Atoh1 sequence (Atoh1(WT) merged to the P2A-CreERT2-hCD2 then to a neomycin cassette inserted such that the 3'UTR was not disrupted. Following successful germline transmission, the mice heterozygous for the targeting construct were crossed onto PGK-Cre line in order to remove both the neo-selection cassette and the endogenous Atoh1 locus at the same time.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • Atoh1-P2A-CreER<T2>,
  • Atoh1<(WT)CreERT2>,
  • Atoh1<(WT)CreERT2>,
  • Atoh1-P2A-CreER<T2>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

Trail: Allele

3 Publication categories

Trail: Allele