Primary Identifier | MGI:2158472 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Gli2 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A lacZ gene and a loxP-flanked neomycin selection cassette replaced 56 bp of exon 2, including the initiation codon. The neomycin selection cassette was removed by Cre mediated recombination in mice by crossing Gli2tm2Alj mice with NLS-cre expressing mice, and selecting for offspring that no longer had the neomycin cassette. |