|  Help  |  About  |  Contact Us

Protein Coding Gene : Mknk2 MAP kinase-interacting serine/threonine kinase 2

Primary Identifier  MGI:894279 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  17347
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables ATP binding activity and protein serine/threonine kinase activity. Involved in intracellular signal transduction and protein phosphorylation. Acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in nuclear body. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; neural retina; salivary gland; and spleen. Orthologous to human MKNK2 (MAPK interacting serine/threonine kinase 2).
PHENOTYPE: Homozygous null mice are viable and fertile with no gross abnormalities. [provided by MGI curators]
  • synonyms:
  • MAP kinase-interacting serine/threonine kinase 2,
  • 2010016G11Rik,
  • RIKEN cDNA 2010016G11 gene,
  • Mnk2,
  • MGI:1916453,
  • Mknk2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For