Primary Identifier | MGI:894279 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 17347 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0) Enables ATP binding activity and protein serine/threonine kinase activity. Involved in intracellular signal transduction and protein phosphorylation. Acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in nuclear body. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; neural retina; salivary gland; and spleen. Orthologous to human MKNK2 (MAPK interacting serine/threonine kinase 2). PHENOTYPE: Homozygous null mice are viable and fertile with no gross abnormalities. [provided by MGI curators] |