Primary Identifier | MGI:3718546 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 100124488 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cellular response to cytokine stimulus; cellular response to lipopolysaccharide; and cellular response to mechanical stimulus. Is expressed in femur; fibula; humerus; and tibia. Orthologous to human MIR511 (microRNA 511). PHENOTYPE: Homozygous null mice show protection from DSS-induced colitis and macrophages show reduced LPS- and Poly I:C-mediated cytokine responses. [provided by MGI curators] |