Primary Identifier | MGI:5430998 | Allele Type | Chemically induced (ENU) |
Gene | Prkra | Inheritance Mode | Recessive |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | ENU induced a T to C mutation in exon 4 introducing an S130P missense mutation. RT-PCR analysis indicated expression levels in the brain of homozygous mice were similar to wild-type. The mutant protein is unable to bind dsRNA. |