Primary Identifier | MGI:1098686 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 217353 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable mechanosensitive monoatomic ion channel activity. Predicted to act upstream of or within monoatomic ion transmembrane transport. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and nuclear membrane. Human ortholog(s) of this gene implicated in epidermodysplasia verruciformis. Orthologous to human TMC6 (transmembrane channel like 6). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and overtly normal with no major defects in T cell subset numbers or function. [provided by MGI curators] |