Primary Identifier | MGI:3612986 | Allele Type | Transgenic |
Attribute String | Transposon concatemer | Gene | TgTn(sb-T2/Onc)76Dla |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A concatemer of sleeping beauty transposable elements each consisting of the inverted repeat direct repeat sequence specific for sleeping beauty transposase flanking splice acceptor sites and poly A signals in both orientations. Between the splice acceptor sites is 5' long terminal repeat sequence from the murine stem cell virus followed by a splice donor site. This construct can create both loss-of-function and gain-of-function mutations. In line 76 the concatemer is integrated into chromosome 1. Around 25 copies of the construct are integrated in this line and the construct is unmethylated. |