| Primary Identifier | MGI:5897323 | Allele Type | Targeted |
| Attribute String | Hypomorph, Modified regulatory region | Gene | Rr167 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 445 bp deletion in intron 2 of Il4 was engineered by replacing the sequence with a loxP site flanked neomycin resistance gene cassette. The neo cassette was removed through subsequent cre-mediated recombination, leaving an allele lacking the 220 bp highly conserved intron enhancer (hcIE). Expression from this allele is greatly reduced compared to wild-type. |
