Primary Identifier | MGI:2182131 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ctsk |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin selection cassette was inserted into exon 7. An absence of transcript generated from this allele was determined by Northern blot and RT-PCR analyses of total bone RNA. Western blot analysis of protein extracts from homozygous mutant bone showed a lack or encoded protein. |