Primary Identifier | MGI:5902578 | Allele Type | Targeted |
Attribute String | Humanized sequence | Gene | Prnp |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 3 was replaced with the corresponding human sequence containing the methionine at position 129 polymorphism. Cre-mediated recombination removed a floxed neomycin resistance cassette inserted into downstream of exon 3. |