Primary Identifier | MGI:6273812 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Rell1 |
Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
Is Recombinase | false | Is Wild Type | false |
Project Collection | IMPC |
molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTTGTTCAGATTGATTCCCT and ACTCCAAATTTATCTGACAT, which resulted in a 323 bp deletion beginning at Chromosome 5 position 63,930,418 bp and ending after 63,930,740 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001221914 (exon 4) and 265 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 130 and early truncation 11 amino acids later. |