Primary Identifier | MGI:96660 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 16491 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables voltage-gated potassium channel activity. Predicted to be involved in action potential and potassium ion transmembrane transport. Located in axon and plasma membrane. Is expressed in brain and heart. Orthologous to human KCNA3 (potassium voltage-gated channel subfamily A member 3). PHENOTYPE: Mice homozygous for a knock-out allele display no apparent immune system defects. Mice homozygous for a different knock-out allele show reduced body weight, increased basal metabolic rate, resistance to diet-induced obesity, increased insulin sensitivity, and altered peripheral glucose metabolism. [provided by MGI curators] |