| Primary Identifier | MGI:894645 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 18693 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables protein kinase C binding activity and signaling receptor binding activity. Involved in receptor clustering. Acts upstream of or within protein targeting. Located in several cellular components, including Golgi apparatus; perinuclear region of cytoplasm; and postsynaptic density. Is expressed in brain; cerebellum Purkinje cell layer; cerebellum molecular layer; cerebral cortex ventricular layer; and cortical plate. Orthologous to human PICK1 (protein interacting with PRKCA 1). PHENOTYPE: Mice homozygous for a null allele show impaired synaptic plasticity and lack of long-term depression; males are infertile due to reduced sperm count and impaired sperm motility, and display small testes and seminiferous tubules, malformed acrosomes, globozoospermia, and male germ cell apoptosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
