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Allele : Clcn7<tm2Tjj> chloride channel, voltage-sensitive 7; targeted mutation 2, Thomas J Jentsch

Primary Identifier  MGI:2387676 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Clcn7
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A lacZ-neo cassette was inserted in-frame into exon 7, resulting in a fusion protein and deletion of exons 8-10. Normal transcripts were not observed in homozygous mutant animals as shown by Northern blot analysis. The fusion protein was detected by Western blot of embryonic fibroblast lysates derived from homozygous mutant embryos.
  • mutations:
  • Insertion
  • synonyms:
  • C7B,
  • Clcn7<->,
  • C7B,
  • Clcn7<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories

Trail: Allele