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Allele : Appl2<tm1.1Test> adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2; targeted mutation 1.1, Joseph Testa
Primary Identifier  MGI:5703918 Allele Type  Targeted
Attribute String  Null/knockout Gene  Appl2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 5. An FRT-flanked neomycin resistance cassette and a 3' loxP site was inserted downstream of exon 5. Cre-mediated recombination removed the selection cassette and exon 5. Western blot analysis confirmed the absence of protein expression in the liver and heart.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Appl2<->,
  • Appl2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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