| Primary Identifier | MGI:5576549 | Allele Type | Chemically induced (ENU) |
| Attribute String | Hypomorph | Gene | Zap70 |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | ENU mutagenesis induced a C to T point mutation that results in amino acid substitution of valine for alanine at position 243 (A243V). This mutation occures in the C-terminal SH2 domain. Flow cytometry confirmed reduced protein expression on CD4+ CD8+ T cells of the thymus and spleen. |
