| Primary Identifier | MGI:6367665 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Myh6-PRKAG2*)H530RBlsg |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene contains the following elements: mouse Myh6 promoter, human PRKAG2 cDNA with a generated c.1589A>G point mutation, and human GH gene 3' UTR (including poly(A) signal). This mutation, which changes histidine codon 530 to an arginine codon (p.His530Arg), is found in some human familial Wolff-Parkinson-White (WPW) syndrome patients. |
