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Publication : Peering through the pore: nuclear pore complex structure, assembly, and function.

First Author  Suntharalingam M Year  2003
Journal  Dev Cell Volume  4
Issue  6 Pages  775-89
PubMed ID  12791264 Mgi Jnum  J:320054
Mgi Id  MGI:6867286 Doi  10.1016/s1534-5807(03)00162-x
Citation  Suntharalingam M, et al. (2003) Peering through the pore: nuclear pore complex structure, assembly, and function. Dev Cell 4(6):775-89
abstractText  Nuclear pore complexes (NPCs) are large proteinaceous assemblies that provide the only known portals for exchanging macromolecules between the nucleus and cytoplasm. This includes the movement of small molecules and the selective, facilitated transport of large proteins and RNAs. Faithful, continuous NPC assembly is key for maintaining normal physiological function and is closely tied to proper cell division. This review focuses on the most outstanding issues involving NPC structure, assembly, and function.
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