First Author | Alt FW | Year | 1992 |
Journal | Immunol Today | Volume | 13 |
Issue | 8 | Pages | 306-14 |
PubMed ID | 1510813 | Mgi Jnum | J:1576 |
Mgi Id | MGI:50103 | Doi | 10.1016/0167-5699(92)90043-7 |
Citation | Alt FW, et al. (1992) VDJ recombination. Immunol Today 13(8):306-14 |
abstractText | The ability of lymphocyte receptor V, D and J gene segments to rearrange generates much of the receptor diversity that is the hallmark of the immune system. Naturally, the mechanisms of immunoglobulin and T-cell receptor gene recombination are of enormous interest. Here, Fred Alt and colleagues review current understanding of the process and speculate on future findings. |