| First Author | Modi WS | Year | 1989 |
| Journal | Am J Hum Genet | Volume | 45 |
| Issue | 5 | Pages | 814-8 |
| PubMed ID | 2573279 | Mgi Jnum | J:19363 |
| Mgi Id | MGI:67529 | Citation | Modi WS, et al. (1989) The human chromogranin A gene: chromosome assignment and RFLP analysis. Am J Hum Genet 45(5):814-8 |
| abstractText | Chromogranin A/secretory protein I (CgA) is a glycoprotein that is stored and released along with peptide hormones and neurotransmitters from several tissues, although its exact function is not known. A cDNA (gene symbol CHGA) clone was used as a probe in Southern blot analyses of human-rodent somatic cell hybrid DNAs. Discordancy analysis allowed confirmation of the assignment of the gene to chromosome 14. These results were extended using in situ chromosome hybridization, and a signal was found at 14q32. BglII digestion of genomic DNA from 28 unrelated Caucasian individuals probed with CHGA detected a two-allele RFLP with allelic frequencies of .34 and .66. |
