Primary Identifier | MGI:4819617 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Trp53 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 4 was replaced with a human exon 4 that represents the arginine variant of the p.R72P polymorphism (SNP rs1042522). A loxP site flanked neomycin resistance gene cassette inserted upstream of exon 2 was removed by Cre-mediated recombination. |