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Protein Domain : Retroviral integrase, C-terminal SH3 domain

Primary Identifier  IPR040903 Type  Domain
Short Name  SH3_11
description  This is the carboxy-terminal domain (CTD) found in retroviral integrase, an essential retroviral enzyme that binds both termini of linear viral DNA and inserts them into a host cell chromosome. The CTD adopts an SH3-like fold. Each CTD makes contact with the phosphodiester backbone of both viral DNA molecules, essentially crosslinking the structure [].

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0 Protein Domain Regions