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Allele : Tg(Pomc)#Low transgene insertion, Malcolm J Low

Primary Identifier  MGI:4833830 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Pomc)#Low
Strain of Origin  (C57BL/6 x CBA)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene contains a tagged 10.2 kb of the mouse gene encompassing three exons, two introns, and 2 kb of the 5' and 3' flanking sequences. The modification involves the insertion of a random 34 bp sequence in the coding sequence of exon 3, allowing for distinguishing transgene transcripts from endogenous transcripts. Six lines were generated, which all show expression in the pituitary, but lines 35 and 36 exhibit ectopic expression in the hippocampal dentate gyrus.
  • mutations:
  • Insertion
  • synonyms:
  • pHalEx2*Tg,
  • pHAL*,
  • pHalEx2*Tg,
  • pHAL*
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele