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Publication : Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues.

First Author  Uchida K Year  1997
Journal  Cytogenet Cell Genet Volume  78
Issue  3-4 Pages  209-12
PubMed ID  9465889 Mgi Jnum  J:51630
Mgi Id  MGI:1331672 Doi  10.1159/000134658
Citation  Uchida K, et al. (1997) Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues. Cytogenet Cell Genet 78(3-4):209-12
abstractText  The murine cytokine inducible SH2-containing (Cis) protein gene (Cish) was recently cloned and shown to have a growth inhibitory function. We have isolated cDNAs coding for its human homologue (CISH) and assigned the gene to 3p21.3 by fluorescence in situ hybridization. Northern blot analysis showed CISH expression in various epithelial tissues including lung and kidney, in which tumors frequently exhibit 3p21.3 deletions.
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