Primary Identifier | MGI:4834769 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(Msx2-cre/ERT)27Alj |
Strain of Origin | Swiss Webster | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A transgenic construct was generated that contained cre/ERT, beta-globin intron, LacZtag, and SV40polyA coding sequences under control of an apical ectodermal ridge (AER)-specific 520 bp Msx2 promoter. The purified construct was injected into Swiss Webster zygotes. Nine founders were generated with eight transmitting the transgene. Four expressed cre/ERT in the apical ectodermal ridge (AER). Studies were performed using one line (no. 27) that showed the strongest expression. |