Primary Identifier | MGI:3800795 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Oxtr |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An frt-flanked neo cassette with a 3' loxP site was inserted downstream of exon 1 and an additional loxP site was inserted downstream of exon 3. Autoradiography with 125-I labeled ornithine vasotocin, an Oxt antagonist, confirmed decreased endogenous and ectopic protein expression. |