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Publication : A human candidate spermatogenesis gene, RBM1, is conserved and amplified on the marsupial Y chromosome.

First Author  Delbridge ML Year  1997
Journal  Nat Genet Volume  15
Issue  2 Pages  131-6
PubMed ID  9020837 Mgi Jnum  J:38108
Mgi Id  MGI:85495 Doi  10.1038/ng0297-131
Citation  Delbridge ML, et al. (1997) A human candidate spermatogenesis gene, RBM1, is conserved and amplified on the marsupial Y chromosome. Nat Genet 15(2):131-6
abstractText  Three genes, RBM1, DAZ and TSPY, map to a small region of the long arm of the human Y chromosome which is deleted in azoospermic men. RBM1, but not DAZ or TSPY, has a Y-linked homologue in marsupials which is transcribed in the testis. This suggests that RBM1 has been retained on the Y chromosome because of a critical male-specific function. Marsupial RBM1 is closely related to human RBM1, but, like the related autosomal gene hnRNPG, lacks the amplification of an exon. This suggests that RBM1 evolved from hnRNPG at least 130 million years ago and has undergone internal amplification in primates, as well as independent amplification in several eutherian lineages.
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