Primary Identifier | MGI:1891751 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 56310 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables transcription coactivator activity and transcription corepressor activity. Involved in several processes, including negative regulation of protein K63-linked ubiquitination; regulation of signal transduction; and regulation of transcription by RNA polymerase II. Located in mitochondrion and nucleus. Part of transcription repressor complex. Orthologous to human GPS2 (G protein pathway suppressor 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality during organogenesis. [provided by MGI curators] |