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Protein Domain : SGSM3, SH3 domain

Primary Identifier  IPR035833 Type  Domain
Short Name  SGSM3_SH3
description  SGSM3 (also known as MAP, RUSC3, or RabGAP5) is expressed ubiquitously and functions as a regulator of small G protein RAP- and RAB-mediated neuronal signalling []. It is involved in modulating NGF-mediated neurite outgrowth and differentiation []. It also interacts with the tumour suppressor merlin and may play a role in the merlin-associated suppression of cell growth []. SGSM3 contains TBC, SH3, and RUN domains.This entry includes the SH3 domain of SGSM3.

0 Child Features

1 Parent Features

3 Protein Domain Regions