Primary Identifier | MGI:1195966 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 18163 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable beta-catenin binding activity and cadherin binding activity. Predicted to be a structural constituent of postsynaptic density. Acts upstream of or within learning; morphogenesis of a branching structure; and regulation of synaptic plasticity. Located in postsynaptic density. Is expressed in several structures, including central nervous system; future brain; lung; sensory organ; and spinal ganglion. Human ortholog(s) of this gene implicated in anxiety disorder; major depressive disorder; and schizophrenia. Orthologous to human CTNND2 (catenin delta 2). PHENOTYPE: Mice homozygous for a reporter allele exhibit abnormal conditioning, spatial learning and coordination behaviors and abnormal long term potentiation. [provided by MGI curators] |