| Type | MGI:General | Description | mice administered the TLR9 ligand CpG to induce cytokine storm syndrome show a similar increase in spleen and liver weight, decrease in WBC counts, areas of inflammatory infiltrates in the liver and percentage of F4/80+CD11b+ liver macrophages as in controls indicting that tissue infiltration by monocytes/macrophages is not affected, however serum ferritin levels are lower and production of inflammatory cytokines is reduced |
