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Protein Coding Gene : Ptpa protein phosphatase 2 protein activator
Primary Identifier  MGI:1346006 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  110854
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including ATP binding activity; protein homodimerization activity; and protein phosphatase 2A binding activity. Predicted to contribute to phosphoprotein phosphatase activity. Predicted to be involved in mitotic spindle organization; positive regulation of apoptotic process; and regulation of protein dephosphorylation. Predicted to be located in nucleoplasm. Predicted to be part of ATPase complex; calcium channel complex; and protein phosphatase type 2A complex. Predicted to be active in cytoplasm and nucleus. Is expressed in embryo and forelimb bud. Human ortholog(s) of this gene implicated in Parkinson's disease 25. Orthologous to human PTPA (protein phosphatase 2 phosphatase activator).
  • synonyms:
  • Ptpa,
  • protein phosphatase 2A activator, regulatory subunit B,
  • RIKEN cDNA 2610042B21 gene,
  • expressed sequence N28142,
  • MGI:2139462,
  • MGC:7129,
  • N28142,
  • MGC:60706,
  • MGI:1923815,
  • expressed sequence C77440,
  • 2610042B21Rik,
  • C77440,
  • protein phosphatase 2 protein activator,
  • Ppp2r4,
  • MGI:2139539
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