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Protein Coding Gene : Hey1 hairy/enhancer-of-split related with YRPW motif 1

Primary Identifier  MGI:1341800 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  15213
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; identical protein binding activity; and sequence-specific DNA binding activity. Involved in several processes, including circulatory system development; nephron development; and regulation of gene expression. Acts upstream of or within several processes, including circulatory system development; osteoblast development; and positive regulation of osteoblast differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; heart; jaw; and sensory organ. Orthologous to human HEY1 (hes related family bHLH transcription factor with YRPW motif 1).
PHENOTYPE: Homozygous null mice are healthy and fertile with no major developmental defects. [provided by MGI curators]
  • synonyms:
  • CHF2,
  • bHLHb31,
  • expressed sequence AI414254,
  • hesr-1,
  • AI414254,
  • HRT1,
  • MGI:2139670,
  • MGI:2139691,
  • Herp2,
  • AI316788,
  • Hey1,
  • expressed sequence AI316788,
  • Hesr1,
  • hairy/enhancer-of-split related with YRPW motif 1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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1 Driver For